What it is
This is a combination capsule holding two different compounds at fixed amounts: 250 mcg of SLU-PP-332 and 50 mg of BAM-15. A mcg is a microgram, one thousandth of a milligram (mg).
SLU-PP-332 is a small molecule studied as an "exercise mimetic" — a compound that switches on some of the same processes inside your cells that physical exercise switches on, particularly the building of more mitochondria, the tiny structures inside cells that turn food into usable energy.
BAM-15 is a mitochondrial uncoupler. Mitochondria normally build up a charge across an internal membrane and then let it flow through a turbine that makes ATP — the molecule your cells spend as energy. BAM-15 lets some of that charge leak back without going through the turbine, so the energy comes out as heat instead. The cell then burns more fuel to keep up. Its own page states this happens without raising heart rate, blood pressure, or body temperature.
Put together, the logic of the pairing is straightforward: one compound builds the machinery, the other makes it run hot.
Information specific to this blend is limited to cycling and dosing instructions — there is no blend-specific benefits list, side effects list, or contraindication list.
Fixed-ratio oral combination: SLU-PP-332 250 mcg + BAM-15 50 mg per capsule.
SLU-PP-332 is a pan-agonist of the estrogen-related receptors (ERRα/β/γ), nuclear receptors downstream of PGC-1α that drive mitochondrial biogenesis, oxidative-phosphorylation gene expression, and fatty-acid oxidation — the endurance-training transcriptional signature, hence "exercise mimetic".
BAM-15 is a mitochondrial protonophore that dissipates the proton-motive force, uncoupling substrate oxidation from ATP synthesis so that respiration accelerates and the surplus leaves as heat. Its standalone page claims this occurs without tachycardia, hypertension, or hyperthermia.
The combination is mechanistically coherent — expand oxidative capacity, then run a controlled leak across it — and the receptor pharmacology above is class background rather than blend-specific data. Blend-specific information covers dosing only.
One dose note worth flagging: the maximum protocol here is 2 capsules, i.e. 100 mg of BAM-15 per day, twice the 50 mg fixed dose on the standalone BAM-15 page.
What it does
No effects specific to the blend have been documented; what is available covers only cycling and dosing.
From the two standalone pages on this site: BAM-15 raises the amount of energy you burn at rest, improves fat metabolism, regulates blood sugar, and increases insulin sensitivity — how well your body responds to its own insulin. SLU-PP-332's own pages describe no effects at all; the exercise-mimetic framing above is background on its class rather than a claim from the site.
The blend guidance that is available is practical, and all of it points to a compound that raises energy expenditure: take it fasted, stay well hydrated, and take electrolytes — sodium, potassium, and magnesium.
No blend-specific pharmacodynamics have been documented. From the standalone BAM-15 page: increased resting energy expenditure, enhanced lipid metabolism and fatty-acid oxidation, glycaemic regulation, improved insulin sensitivity, senolytic and anti-inflammatory activity. The SLU-PP-332 pages state no effects; the ERR mechanism is class background.
The blend's own guidance covers administration, and it is more specific than the standalone pages on two points: a fasted window of 1.5–2 hours either side of a meal, and explicit instruction to maintain hydration and repletion of sodium, potassium, and magnesium. Both are consistent with a sustained increase in expenditure and with the fluid and electrolyte turnover that accompanies it.
Benefits
Evidence grades: what the labels mean
- Human trials Supported by randomised or placebo-controlled human trials.
- Limited human data Some human evidence, such as pilot studies, case reports or observational data, but no controlled trials.
- Animal or lab only Shown in animal or cell studies only; not yet tested in people.
- Anecdotal No published studies; based on user reports or theory.
Each grade reflects the strongest published support for that specific claim, not for the compound as a whole.
- No benefits specific to the blend have been documented; only cycling and dosing instructions are available.Anecdotal
- From the standalone BAM-15 page: improves how the body processes and burns fat.Animal or lab only
- From the standalone BAM-15 page: helps regulate blood sugar.Animal or lab only
- From the standalone BAM-15 page: increases insulin sensitivity.Animal or lab only
- From the standalone BAM-15 page: increases the amount of energy you burn at rest.Animal or lab only
- From the standalone BAM-15 page: weight loss.Animal or lab only
- From the standalone BAM-15 page: senolytic and anti-senescence effects — inhibiting, reversing, or clearing out senescent cells, which are aged cells that have stopped dividing and can contribute to ageing and age-related disease.Anecdotal
- From the standalone BAM-15 page: anti-inflammatory.Animal or lab only
- The SLU-PP-332 pages on this site list no benefits of their own, so nothing can be carried across for that half of the capsule.Anecdotal
- No blend-specific benefits have been documented.Anecdotal
- Carried from the standalone BAM-15 page: enhanced lipid metabolism and fatty-acid oxidation; blood-glucose regulation; increased insulin sensitivity; increased resting energy expenditure; weight loss; senolytic / anti-senescence activity; anti-inflammatory effects.Anecdotal
- Neither SLU-PP-332 page carries a benefits list, so the ERR arm contributes nothing citable.Anecdotal
Reconstitution and dosing
Each pill holds 250 mcg of SLU-PP-332 and 50 mg of BAM-15.
The standard protocol is one pill per day, in the morning. The maximum protocol is two pills per day — one immediately on waking, the second no later than 3pm.
Run a 4 to 6 week cycle, then take 2 to 4 weeks off.
Take it fasted, meaning 1.5 to 2 hours before or after a meal. Stay well hydrated. Electrolytes help — specifically sodium, potassium, and magnesium.
One thing to be aware of: at two pills a day you are taking 100 mg of BAM-15, which is double the 50 mg a day on the standalone BAM-15 page.
Fixed ratio, 250 mcg SLU-PP-332 + 50 mg BAM-15 per capsule. Standard 1 capsule AM; maximum 2 capsules, first immediately on waking and second by 3pm.
Cycle 4–6 weeks with a 2–4 week washout. This sits between the component pages: SLU-PP-332 oral runs 4–8 weeks, BAM-15 runs 2–4 weeks. The blend's 4–6 weeks therefore exceeds the standalone BAM-15 cycle ceiling.
Fasted, defined here as 1.5–2 hours either side of a meal. Hydration is instructed, with sodium, potassium, and magnesium repletion.
Dose-comparison flag: the maximum protocol supplies 100 mg/day BAM-15 against the standalone page's fixed 50 mg/day, and 500 mcg/day SLU-PP-332 against the standalone oral page's 300–600 mcg/day range. The BAM-15 arm is the one that steps outside its own page's documented dose; the SLU-PP-332 arm does not.
Capsules — 250 mcg SLU-PP-332 + 50 mg BAM-15 per pill
Cycle: 4–6 week cycle followed by a 2–4 week washout · Frequency: Take while fasted (1.5–2 hours before or after a meal); remain well hydrated; electrolytes help — sodium, potassium, magnesium
| When | Dose | How often |
|---|---|---|
| Standard dosing | 1 pill (250 mcg SLU-PP-332 + 50 mg BAM-15) | once per day, in the AM |
| Maximum dosing | 2 pills (500 mcg SLU-PP-332 + 100 mg BAM-15) | daily total, split across 2 doses — one immediately on waking, the second by 3pm |
Who should avoid it
- No contraindications have been documented for the blend or for either standalone component. Nothing can be carried across. That is an absence of documentation, not evidence that this is safe for everyone.
- From the standalone SLU-PP-332 oral page: the 1,000 mcg SLU-PP-332 capsules are not for first-time users. This blend contains 250 mcg per capsule, so the maximum protocol here gives 500 mcg a day, which stays below that threshold.
- No information is available on pregnancy, breastfeeding, or use in children.
- The maximum protocol delivers 100 mg of BAM-15 a day, double the 50 mg the standalone BAM-15 page uses. Worth knowing before going to two pills.
- Talk to a doctor before starting, and go through your full medication list with them.
- No contraindication list exists for the blend or either component — nothing is available to carry across. Treat as missing documentation, not a clean profile.
- From the standalone SLU-PP-332 oral page: 1,000 mcg SLU-PP-332 capsules are restricted to non-naive users. At 250 mcg per capsule, this blend's 2-capsule maximum is 500 mcg/day and stays under that gate.
- The 2-capsule maximum is 100 mg/day of BAM-15, twice the standalone fixed dose, and tolerability at that level has not been characterised.
- No data are available on pregnancy, lactation, paediatric use, cardiovascular disease, thyroid disease, or thermoregulatory impairment.
Side effects
- No side effects have been documented for the blend or for either standalone component.
- The nearest thing available is the standalone BAM-15 page's claim about what does not happen: no increase in heart rate, blood pressure, or body temperature.
- The hydration and electrolyte instructions are the closest thing to a warning: stay well hydrated, and take sodium, potassium, and magnesium.
- The instruction to dose in the morning, with a second pill no later than 3pm, is the usual precaution against sleep disturbance from an energy-raising compound.
- No side-effect list exists for the blend or either component.
- The only tolerability statement available is negative, carried from the standalone BAM-15 page: no increase in heart rate, blood pressure, or body temperature.
- The hydration and sodium/potassium/magnesium instruction functions as implicit tolerability guidance.
- The AM dosing and 3pm cut-off on the second capsule imply a sleep-disturbance concern.
User reports
User reports are individual experiences submitted by site visitors. They are not medical advice, are not verified for accuracy, and do not reflect Amino Reference's views. Read the evidence section above and talk to a clinician. Full disclaimer.
Stacking
One of the two compounds in this capsule, sold on its own. Read it if you want to run the two separately, or to understand the cycling rules for that half.
The ERR-agonist component as a standalone, at 300 mcg or 1,000 mcg per capsule against the 250 mcg here, with its own 4–8 week cycle and mandatory fasted dosing.
The other compound in this capsule, sold on its own at the same 50 mg strength. Its entry covers the benefits and mechanism for this half of the blend.
The uncoupler component as a standalone at the identical 50 mg strength, but with a shorter 2–4 week cycle. That entry holds the only documented effects for either arm of this blend.
Dosing figures have been reviewed and units are recomputed from the stated protocol.